Mice
NCI Mouse Repository
The NCI Mouse Repository
is a resource for mouse cancer models and associated strains. The repository
makes strains freely available to all members of the scientific
community (academic, non-profit, and commercial). Strains are maintained as
live colonies or cryoarchived as frozen embryos. Up to three breeder pairs may
be ordered from live colonies. Cryoarchived strains are supplied as frozen
embryos or recovery of live mice by the NCI Repository may be requested.
JAX® Mice
JAX® Mice are produced according to the highest
standards of animal health and genetic quality. The collection of more than
3,100 strains expands each year. JAX® Mice offers a single source for both common
inbreds as well as thousands of specialized disease models and
genetically engineered strains.
Mutant Mouse
Regional Resource Centers (MMRRC)
National Network
The MMRRC program is supported by the National Center for Research Resources
(NCRR) at the National Institutes of Health (NIH, DHHS). The purpose of the
program is to ensure the continued availability of scientifically valuable,
genetically engineered mice and to distribute these mice to qualified
researchers studying human and animal biology and disease. A national network
of regional breeding and distribution facilities serves as NIH's premier
repository of spontaneous and induced mutant mouse lines.
International
Mouse Strain Resource (IMSR)
The IMSR is a searchable online database of mouse
strains and stocks available worldwide, including inbred, mutant, and
genetically engineered mice. The goal of the IMSR is to assist the
international scientific community in locating and obtaining mouse resources
for research.
International Knockout Mouse Consortium (IKMC)
The IKMC is an
international consortium that is developing and distributing knockout mouse
models. This project aims to generate null
alleles for most mouse genes, in a standard mouse ES (embryonic stem) cell
background. These cells can then be used for further development of appropriate
animal models. Project details and model searches can be explored, and access to the
cells and mice is provided from the KOMP, or
Knock Out Mouse Project, repository.
Charles River
Laboratories
Charles River Laboratories has provided research
models and laboratory animal support services, pre-clinical services, and
clinical services to the biomedical market for more than half a century. Research
model animals include stocks, strains and mutant animals, some of
which are specifically classified as disease
models.
Harlan™
For decades, Harlan has provided stocks, strains and mutant animals for many aspects of biomedical
research in many countries.
Inbred, outbred, mutant and transgenics models of various species are
available. Models are available for a many purposes, some of which are
classified by research use topic
areas.
Taconic
Taconic employs over 50 years of expertise to provide
genetically-defined, high quality rodent
models to the biomedical research community. Traditional models, induced models, and transgenic models are all
available. Experts are available to
review needs, discuss desired outcomes, and recommend the rat or mouse model
that will enable you to conduct the most efficient and reliable in vivo study.
The information included in this section includes best practices and available resources, but does not intend to endorse any particular manufacturer’s products.