Animal Husbandry for Mice
Experience with breeding and maintenance of laboratory mouse colonies dates back to the beginning of the twentieth century. Continuous improvements in the physical and technological aspects of mouse husbandry have led to the development of excellent strategies, tools, and environmental conditions for mouse models.
General considerations of the features of appropriate laboratory animal care can be found in the Animal Environment, Housing, and Management chapter of the Guide for the Care and Use of Laboratory Animals, a primary reference book in this arena. However, there are specific issues for individual species and even strains that should be considered. In the case of mice, some strains may be more or less aggressive than others. Among breeding stock, some animals may be inattentive mothers, for example, and offspring may require special interventions. Animals with compromised immune systems or other genetic alterations may have special health issues and needs. Dietary requirements may vary for both the basic strain characteristics, or for experimental situations. For more reference material specific to mouse colony maintenance, The Laboratory Mouse text may be of assistance.
The information included in this section includes best practices and available resources, but does not intend to endorse any particular manufacturer’s products.