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Mouse - Skin - MC02-0468.pff

MC02-0468.pff image submitted by Robert Cardiff

Image Name: MC02-0468.pff

Image Annotation: Amelanotic spindle and epithelioid cell tumor from a Tyr-RasV12G Ink4a-/- mouse. This higher power view reveals the spindle and epithelioid nature of the tumor cells, nuclear atypia, and numerous mitoses. Large eosinophilic intracytoplasmic inclusions are present that resemble the Kamino bodies seen in human Spitz nevi. However, the numerous mitoses and the invasive nature of the tumor are those of a malignant process. Marcus Bosenberg

Staining Method: Hematoxylin and Eosin Staining Method

Species: Mouse
Strain: C57BL/6

Organ: Skin


Gene: Ink4a and Tyrosine-RasV12G


Image donated by: Robert Cardiff