Skip Navigation
National Cancer Institute U.S. National Institutes of Health www.cancer.gov
Personal tools
You are here: Home caIMAGE Mouse Integument System Skin Mouse - Skin - MC02-0468.pff
Document Actions

Mouse - Skin - MC02-0468.pff

MC02-0468.pff image submitted by Robert Cardiff

Image Name: MC02-0468.pff

Image Annotation: Amelanotic spindle and epithelioid cell tumor from a Tyr-RasV12G Ink4a-/- mouse. This higher power view reveals the spindle and epithelioid nature of the tumor cells, nuclear atypia, and numerous mitoses. Large eosinophilic intracytoplasmic inclusions are present that resemble the Kamino bodies seen in human Spitz nevi. However, the numerous mitoses and the invasive nature of the tumor are those of a malignant process. Marcus Bosenberg

Staining Method: Hematoxylin and Eosin Staining Method

Species: Mouse
Strain: C57BL/6

Organ: Skin
Diagnosis:

Gender:

Promoter:
Gene: Ink4a and Tyrosine-RasV12G

Publication:

Image donated by: Robert Cardiff