Mouse - Skin - skin_019.tif
Image Name: skin_019.tif
Image Annotation: TRP1 immunoperosidase staining of the remnant of an amelanotic spindle and epithelioid cell tumor from a Tyr-rtTA tetOp-RasV12G Ink4a-/- mouse that had been fed doxycycline and then withdrawn from doxycycline for a period of 12 days. Scattered TRP1-positive cells with small amounts of cytoplasm are present in the dermis and at the overlying epidermal/dermal junction.
Staining Method: For tyrosinase related protein 1
Diagnosis: Amelanotic Spindle and Epithelioid Melanoma
Gene: tetOpRasV12G, Cdkn2a-/-
Image donated by: Marcus Bosenberg