Image Name: skin_019.tif

Image Annotation: TRP1 immunoperosidase staining of the remnant of an amelanotic spindle and epithelioid cell tumor from a Tyr-rtTA tetOp-RasV12G Ink4a-/- mouse that had been fed doxycycline and then withdrawn from doxycycline for a period of 12 days. Scattered TRP1-positive cells with small amounts of cytoplasm are present in the dermis and at the overlying epidermal/dermal junction.

Staining Method: For tyrosinase related protein 1

Species: Mouse
Strain: FVB

Organ: Skin
Diagnosis: Amelanotic Spindle and Epithelioid Melanoma

Gender:

Promoter: Tyrosinase-rtTa
Gene: tetOpRasV12G, Cdkn2a-/-

Publication: 10440378

Image donated by: Marcus Bosenberg