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Mouse - Skin - skin_033.tif

skin_033.tif submitted by Marcus Bosenberg

Image Name: skin_033.tif

Image Annotation: Cheek skin from transgenic mice expressing MycER in suprabasal epidermal keratinocytes following 19 days of topical application of 4-hydroxytamoxifen (1 mg/day). The epidermis is hyperplastic (7 to 12 cells in thickness), hyperkeratotic, and parakeratotic. Nuclear atypia is present and involves the full thickness of the hyperplastic epidermis.

Staining Method: Hematoxylin and Eosin Staining Method

Species: Mouse
Strain: CBA x C57BL/6

Organ: Skin
Diagnosis: Squamous Cell Carcinoma in Situ of the Skin


Promoter: human involucrin
Gene: MycER

Publication: 10360173

Image donated by: Marcus Bosenberg