Mouse - Skin - skin_035.tif
Image Name: skin_035.tif
Image Annotation: Poorly differentiated spindle cell squamous cell carcinoma arising in a HK1-p53R172H mouse treated with a two-stage carcinogenesis protocol. The tumor is nodular and is composed of pleomorphic spindle cells which are better seen at higher magnification (see skin_34).
Staining Method: Hematoxylin and Eosin Staining Method
Diagnosis: Spindle-cell Squamous Cell Carcinoma of the Murine Skin
Promoter: Human keratin 1
Gene: Mouse mutant p53 (Arg175His)
Image donated by: Marcus Bosenberg