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Mouse - Skin - skin_044.tif

skin_044.tif submitted by Marcus Bosenberg

Image Name: skin_044.tif

Image Annotation: Sebaceous adenoma arising in a transgenic mouse with epidermal c-myc expression treated with a two-stage chemical carcinogenesis protocol. Note the peripheral rim of primitive basaloid cells surrounding differentiated sebocytes. Features of sebaceous carcinoma are not present, but would include marked nuclear atypia, numerous mitoses, and necrosis.

Staining Method: Hematoxylin and Eosin Staining Method

Species: Mouse
Strain: FVB x ICR

Organ: Skin
Diagnosis: Sebaceous Adenoma of the Skin


Promoter: Human keratin 14
Gene: Human c-myc2

Publication: 11381265

Image donated by: Marcus Bosenberg