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Mouse - Skin - skin_045.tif

skin_045.tif submitted by Marcus Bosenberg

Image Name: skin_045.tif

Image Annotation: Malignant spindle cell neoplasm arising in a C3H mouse treated with Kodacel-filtered FS40 lamps (see also skin_46). The overlying squamous epithelium is hyperplastic and atypical with areas focally amounting to squamous cell carcinoma in situ. The presence of a preneoplastic /neoplastic squamous lesion raises the possibility that the underlying malignant spindle cell neoplasm is a spindle cell carcinoma, however, a definitive origin of the spindled cells (see skin_48) from the overlying epidermis was not identified.

Staining Method: Hematoxylin and Eosin Staining Method

Species: Mouse
Strain: C3H

Organ: Skin
Diagnosis: Unclassified Malignant Spindle Cell Neoplasm of the Skin



Publication: 10435637

Image donated by: Marcus Bosenberg