Mouse - Skin - skin_070.tif
Image Name: skin_070.tif
Image Annotation: Hyperplasia+adenocarcinoma. TRAMP with Invasive adenocarcinoma of the prostate. Whole slide image of the prostate of a transgenic probasin:SV40-Tag (TRAMP) male mouse provide from the collection of Dr. Ronald Herbert. The seminal vesicles are dilated with the phylloides type lesions . The prostate has a generalized atypical hyperplasia of the luminal epithelium. One area has a small focus of microinvasive carcinoma. One or two areas of microinvasive adenocarcinoma are present. These irregular glands invade the stroma around the ducts and have a high mitotic rate with pleomorphic nuclei with an open chromatin pattern.
Staining Method: Hematoxylin and Eosin Staining Method
Diagnosis: Moderately-differentiated Squamous Cell Carcinoma of the Skin
Promoter: Human keratin 14
Gene: Human HPV16 early region
Image donated by: Marcus Bosenberg