Mouse - Skin - skin_078.tif
Image Name: skin_078.tif
Image Annotation: S100 immunoperoxidase stain of human breast skin grafted onto a SCID mouse after 7 months of treatment with UV irradiation three times per week and a single DMBA treatment reveals junctional melanocytic hyperplasia. S100 stains both melanocytes and Langerhans's cells within the epidermis, and while the latter tend to be located suprabasally, use of a melanocytic-specific stain such as TRP1 (or a Masson-Fontana stain for melanin in non-albino mice) is more definitive.
Staining Method: Family of calcium binding proteins
Diagnosis: Junctional Melanocytic Hyperplasia
Image donated by: Marcus Bosenberg