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Mouse - Skin - skin_108.tif

skin_108.tif submitted by Marcus Bosenberg

Image Name: skin_108.tif

Image Annotation: Malignant basaloid follicular neoplasm arising as a nodular tumor on the back of a K5-GLI1 transgenic mouse. This tumor bears some resemblance to the tumor depicted in skin_105-107, with cords of basaloid cells separated by dense eosinophilic material, but the majority of this tumor is more poorly differentiated. The jigsaw puzzle-like architecture is less well developed and the central portion of the tumor is necrotic and cystic.

Staining Method: Hematoxylin and Eosin Staining Method

Species: Mouse
Strain: B6.CBA

Organ: Skin
Diagnosis: Cylindroma Type of Basaloid Follicular Neoplasm of the Skin

Gender: Male

Promoter: Bovine keratin 5
Gene: Human Gli1

Publication: 10725363

Image donated by: Marcus Bosenberg