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Mouse - Skin - skin_130.tif

skin_130.tif submitted by Marcus Bosenberg

Image Name: skin_130.tif

Image Annotation: Basaloid follicular neoplasm arising in a Patched +/- mouse treated with ionizing radiation. The tumor is composed of cords of basaloid cells and as in skin_127, contains foci resembling germinative follicles. In addition, a keratocyst that contains several hair fragments is present. The overall features are similar to human trichoblastomas, however keratocyst are more typically seen in human trichoepitheliomas. A slightly different histologic pattern is present in other areas of this tumor (see skin_131).

Staining Method: Hematoxylin and Eosin Staining Method

Species: Mouse
Strain: C57BL/6 x DBA/2J

Organ: Skin
Diagnosis: Trichoblastoma Type of Basaloid Follicular Neoplasm of the Skin

Gender:

Promoter:
Gene: Patched +/-

Publication: 10545995

Image donated by: Marcus Bosenberg