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Mouse - Skin - skin_151.tif

skin_151.tif submitted by Marcus Bosenberg

Image Name: skin_151.tif

Image Annotation: Well differentiated squamous cell carcinoma arising in a squamous papilloma on the back of a Sencar mouse treated with a two-step chemical carcinogenesis protocol. This lesion (see also skin_148 and skin_149) developed in the context of a squamous papilloma, but exhibits widespread underlying stromal fibrosis (desmoplasia). This pattern is frequently seen in human verrucous squamous cell carcinoma, which also has a characteristically broad invasive front without evidence of microinvasion.

Staining Method: Hematoxylin and Eosin Staining Method

Species: Mouse
Strain: SENCAR

Organ: Skin
Diagnosis: Well-differentiated Squamous Cell Carcinoma of the Skin



Publication: 8242866

Image donated by: Marcus Bosenberg