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Phenotyping Rabbit Cancer Models

Rabbit models of cancer have been established for decades, and investigations of melanoma models, pleural cancer, and papilloma have support from the scientific literature.  Researchers interested in these models should explore the work of researchers in this field to learn more about normal and abnormal tissue characterizations.

Guidance on the phenotypic characteristics of rabbits may be obtained from general texts such as The Laboratory Rabbit, or from pathology or toxicology resources such as Animal Models in Toxicology.

As with other models which don’t have the support of a completed genomic sequencing project at this time, the rabbit model system relies more on physical phenotyping than molecular phenotyping.  Increasing emphasis and support for Rabbit Biotechnology should make available techniques such as microarray analysis and sequencing strategies for the rabbit research community as well.