Because of their similarity to human biology, research in monkeys can provide insights about treatments that may benefit humans. One example of this is immunotherapy that has been explored in B-cell malignancy. Pre-clinical work on potential anti-angiogenesis treatments have been performed in monkeys. Vaccination as a treatment strategy has been evaluated in rhesus monkeys. The role of diet in the onset of cancer can be examined in monkeys as well.
Models of melanoma in non-human primates that more closely mimic human cases could benefit researchers. Identification of squamous cell carcinomas in non-human primates, and gastrointestinal tumors in various species, may offer a path to further study as well. Marmosets have provided a potential route of investigation for intestinal adenocarcinoma.
The pharmacokinetics of drug treatments in larger animals offers opportunity for understanding drug behavior that may translate to humans more effectively. In addition, the opportunity for longer term studies is beneficial in these animals. Gene therapy as a possible intervention strategy can be explored in non-human primates and in dogs. The availability of stem cells for various medical strategies now includes pigs as well.
Veterinary oncology, including immunotherapy strategies, explored in cats and dogs could yield advances for human and animal patients.