Acquiring Models



NCI Mouse Repository
The NCI Mouse Repository is a resource for mouse cancer models and associated strains. The repository makes strains freely available to all members of the scientific community (academic, non-profit, and commercial). Strains are maintained as live colonies or cryoarchived as frozen embryos. Up to three breeder pairs may be ordered from live colonies. Cryoarchived strains are supplied as frozen embryos or recovery of live mice by the NCI Repository may be requested.

JAX® Mice
JAX® Mice are produced according to the highest standards of animal health and genetic quality. The collection of more than 3,100 strains expands each year. JAX® Mice offers a single source for both common inbreds as well as thousands of specialized disease models and genetically engineered strains.

Mutant Mouse Regional Resource Centers (MMRRC) National Network
The MMRRC program is supported by the National Center for Research Resources (NCRR) at the National Institutes of Health (NIH, DHHS). The purpose of the program is to ensure the continued availability of scientifically valuable, genetically engineered mice and to distribute these mice to qualified researchers studying human and animal biology and disease. A national network of regional breeding and distribution facilities serves as NIH's premier repository of spontaneous and induced mutant mouse lines.

International Mouse Strain Resource (IMSR)
The IMSR is a searchable online database of mouse strains and stocks available worldwide, including inbred, mutant, and genetically engineered mice. The goal of the IMSR is to assist the international scientific community in locating and obtaining mouse resources for research.


International Knockout Mouse Consortium (IKMC)

The IKMC is an international consortium that is developing and distributing knockout mouse models. This project aims to generate null alleles for most mouse genes, in a standard mouse ES (embryonic stem) cell background. These cells can then be used for further development of appropriate animal models. Project details and model searches can be explored, and access to the cells and mice is provided from the KOMP, or Knock Out Mouse Project, repository.

Charles River Laboratories
Charles River Laboratories has provided research models and laboratory animal support services, pre-clinical services, and clinical services to the biomedical market for more than half a century. Research model animals include stocks, strains and mutant animals, some of which are specifically classified as disease models.   

For decades, Harlan has provided stocks, strains and mutant animals for many aspects of biomedical research in many countries. Inbred, outbred, mutant and transgenics models of various species are available. Models are available for a many purposes, some of which are classified by research use topic areas.

Taconic employs over 50 years of expertise to provide genetically-defined, high quality rodent models to the biomedical research community. Traditional models, induced models, and transgenic models are all available. Experts are available to review needs, discuss desired outcomes, and recommend the rat or mouse model that will enable you to conduct the most efficient and reliable in vivo study.

The information included in this section includes best practices and available resources, but does not intend to endorse any particular manufacturer’s products.